In hypothyroidism, myxedema is best described as which of the following?

In hypothyroidism, myxedema is best described as which of the following?

• A. Soft edema of the legs
• B. Hard, pitting edema of the face
• C. Non-pitting edema of the hands
• D. Edema is not a feature

Answer: (B)

Myxedema reflects a buildup of mucopolysaccharides in the dermis from severe hypothyroidism, causing a doughy, non-pitting edema. This type of swelling does not indent with pressure, which distinguishes it from ordinary pitting edema. It often involves the face and hands. Among the descriptions given, non-pitting edema of the hands best fits the characteristic pattern of myxedema. Edema in hypothyroidism is a real feature, but it is non-pitting rather than hard and pitting.

Myxedema reflects a buildup of mucopolysaccharides in the dermis from severe hypothyroidism, causing a doughy, non-pitting edema. This type of swelling does not indent with pressure, which distinguishes it from ordinary pitting edema. It often involves the face and hands. Among the descriptions given, non-pitting edema of the hands best fits the characteristic pattern of myxedema. Edema in hypothyroidism is a real feature, but it is non-pitting rather than hard and pitting.